Understanding how cells move in response to different signals
Cell Migration Control through Modulation of Multiple Directional Cues
This study is looking at how cells move in different environments that mimic the natural surroundings in our bodies, which could help us understand important processes like healing wounds and how cancer spreads.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa State University NIH-funded |
| Lab location | 1 site (Ames, United States) |
| Project ID | NIH-10899459 on NIH RePORTER |
What this research studies
This research investigates how cells migrate by using specially engineered environments that mimic the extracellular matrix. By controlling the structure and mechanics of this matrix, the study aims to uncover how cells respond to various directional cues, which is crucial for processes like wound healing and cancer spread. The researchers will explore how cells integrate multiple signals, such as stiffness and fiber alignment, to make decisions about their movement. This could lead to a better understanding of cell behavior in both healthy and diseased states.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve abnormal cell migration, such as cancer patients or those with chronic wounds.
Not a fit: Patients with conditions unrelated to cell migration or those not currently undergoing treatment for cancer or wound healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for conditions involving abnormal cell migration, such as cancer and chronic wounds.
How similar studies have performed: Previous research has shown success in understanding individual directional cues in cell migration, but this approach to integrating multiple cues is relatively novel.
Where this research is happening
Ames, United States
- Iowa State University — Ames, United States (Active)
Researchers
- Principal investigator: Schneider, Ian Christopher — Iowa State University
- Study coordinator: Schneider, Ian Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.