Understanding how cells move and develop during early human development
Official title: Regulation of mesoderm fate patterning through multiscale dynamics
Funded at University of Chicago · NIH-11070678 · Data updated 2026-11-12
This study is looking at how certain cells in early human development move and work together to form tissues, using a special lab model to better understand how they respond to their surroundings.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31GM157880-01 |
| Project ID | NIH-11070678 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in the underlying mechanisms of human development and potential applications in regenerative therapies.
✕Less likely to help
Patients with established tissue damage or conditions unrelated to developmental processes may not benefit from this research.
What this research studies
This research investigates the complex processes involved in early human development, particularly focusing on how mesoderm cells behave and migrate during gastrulation. By using an in vitro gastruloid model, the study aims to explore how cells interpret their changing environment to regulate their functions and contribute to tissue formation. The research challenges traditional views of embryonic development by examining the dynamic interactions between cell movement and their surroundings, providing insights into the mechanisms that govern tissue organization.
Why it matters
Potential benefit: If successful, this research could lead to advancements in regenerative medicine and tissue engineering by improving our understanding of how tissues form and develop.
How similar studies have gone: Other research has shown success in understanding cellular dynamics during development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Johnson, Amanda — University of Chicago
- Study coordinator: Johnson, Amanda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.