Understanding how cells move and change shape using machine learning
Unraveling heterogeneity of molecular mechanisms in cellular motility and morphodynamics by machine learning
['FUNDING_OTHER'] · BOSTON CHILDREN'S HOSPITAL · NIH-10842697
This study is looking at how cells move and change shape using advanced technology to analyze live images, which could help us understand diseases like cancer and improve treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10842697 on ClinicalTrials.gov |
What this research studies
This research investigates the complex ways in which cells move and change shape by utilizing advanced machine learning techniques to analyze live cell imaging data. By capturing high-resolution images of cells in real-time, the study aims to uncover the underlying mechanisms that drive cellular motility and morphodynamics. The approach focuses on addressing the challenges posed by the variability in cellular behavior, allowing for a more nuanced understanding of how cells function under different conditions. Patients may benefit from insights gained into cellular processes that could inform treatments for diseases involving cell migration, such as cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve cellular motility issues, particularly those related to cancer or other diseases characterized by abnormal cell movement.
Not a fit: Patients with stable conditions that do not involve cellular motility or morphology may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of diseases related to abnormal cell movement, such as cancer metastasis.
How similar studies have performed: Other research has shown promise in using machine learning to analyze cellular behavior, indicating that this approach could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, KWONMOO — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: LEE, KWONMOO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.