Understanding how cells move and change direction
Official title: Investigating the role of signaling feedback in directed cell migration
Funded at Weill Medical Coll of Cornell Univ · NIH-10997103 · Data updated 2026-11-12
This study is looking at how cells move around in the body, which is really important for healing wounds and fighting off infections, and it aims to understand how certain signals help cells change direction when they move, which could help us learn more about diseases where this movement goes wrong.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2027 |
| Funding year | 2024 |
| Award (this year) | $73,828 |
| NIH project number | 1F32GM156014-01 |
| Project ID | NIH-10997103 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve impaired cell migration, such as chronic wounds or certain cancers.
✕Less likely to help
Patients with conditions unrelated to cell migration or those not experiencing any migration-related issues may not benefit from this research.
What this research studies
This research investigates the mechanisms that control how cells migrate, which is essential for processes like wound healing and immune response. By focusing on specific signaling pathways, such as PI3K, Ras, and Rac, the study aims to uncover how cells integrate feedback to change direction during movement. The research involves detailed experiments to analyze the roles of these pathways and their interactions, providing insights into the fundamental processes of cell behavior. This knowledge could have implications for understanding various diseases where cell migration is disrupted.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing wound healing and treating diseases related to abnormal cell migration.
How similar studies have gone: Previous research has shown success in understanding cell signaling pathways, making this approach promising for further discoveries.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Pfannenstein, Alexander — Weill Medical Coll of Cornell Univ
- Study coordinator: Pfannenstein, Alexander
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.