Understanding How Cells Make Proteins
Ribosome Structure and Function
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA SANTA CRUZ · NIH-11054558
This project helps us understand the tiny machines in our cells, called ribosomes, that build all the proteins our bodies need.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA CRUZ (nih funded) |
| Locations | 1 site (SANTA CRUZ, UNITED STATES) |
| Trial ID | NIH-11054558 on ClinicalTrials.gov |
What this research studies
Our bodies rely on ribosomes to create proteins, which are essential for every function, from fighting infections to building tissues. This work explores the intricate dance of how ribosomes read genetic instructions and assemble proteins, ensuring accuracy and efficiency. We use advanced techniques like biochemistry and structural imaging to see these processes up close. By uncovering these fundamental mechanisms, we hope to lay the groundwork for new ways to address diseases where protein production goes wrong.
Who could benefit from this research
Good fit: This foundational research does not directly involve patients, but future studies building on this knowledge could potentially benefit individuals with conditions related to protein synthesis errors or viral infections.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: A deeper understanding of how ribosomes work could lead to new strategies for developing medicines that target specific diseases, including viral infections like AIDS.
How similar studies have performed: This project builds upon previous discoveries about ribosome movement and structure, using new methods to explore additional intermediate states.
Where this research is happening
SANTA CRUZ, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA CRUZ — SANTA CRUZ, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NOLLER, HARRY F — UNIVERSITY OF CALIFORNIA SANTA CRUZ
- Study coordinator: NOLLER, HARRY F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus