Understanding How Cells Maintain Healthy DNA
Mechanisms of Genome Stability
['FUNDING_OTHER'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11171475
This research explores how our cells accurately copy their DNA and respond to damage, which is important for preventing diseases like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-11171475 on ClinicalTrials.gov |
What this research studies
Our bodies rely on cells to accurately copy their genetic material, DNA, and fix any damage that occurs. This project looks closely at specific proteins, called ORC and ORCA, that are essential for starting DNA copying and organizing our genetic information. We want to understand how these proteins help cells grow, divide, and survive properly. By studying these fundamental processes, we hope to uncover why mistakes happen that can lead to serious health issues.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation but aims to benefit individuals affected by or at risk for cancers in the long term.
Not a fit: Patients seeking immediate new treatments or clinical trial opportunities would not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how cancers develop and potentially identify new targets for future treatments.
How similar studies have performed: This research builds upon decades of work by the principal investigator and others in understanding the fundamental mechanisms of cell cycle progression and genome stability.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRASANTH, SUPRIYA G — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: PRASANTH, SUPRIYA G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers