Understanding How Cells Fight Viruses
Defining the Biology of the ADAR1-RISC Complex
This research explores a newly discovered way our cells protect themselves from viral infections, aiming to find new strategies to help us stay healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11097182 on NIH RePORTER |
What this research studies
Our bodies have amazing ways to fight off viruses, and this project focuses on a recently found defense system within our cells. We are learning more about a specific group of proteins, called the ADAR-RISC Complex, that quickly responds when a virus tries to infect a cell. By understanding how this complex works and what it does, we hope to uncover new insights into our natural defenses. This knowledge could help us develop better ways to prevent and treat viral illnesses in the future.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation, but future clinical applications would target individuals susceptible to or suffering from viral infections.
Not a fit: Patients not affected by viral infections or those seeking immediate treatment options may not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this research could lead to a deeper understanding of how our bodies naturally fight viruses, potentially opening doors for new antiviral treatments or prevention methods.
How similar studies have performed: While the specific ADAR-RISC complex is a relatively new area of focus, other studies have successfully identified various cellular defense mechanisms against viruses, providing a foundation for this work.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Tenoever, Benjamin R. — New York University School of Medicine
- Study coordinator: Tenoever, Benjamin R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.