Understanding how cells divide correctly
Chemical Biology of Cell Division
This study is looking at how cells divide properly to help prevent problems like cancer, and it's for anyone interested in understanding how we can stop mistakes during this important process by using special tools to watch it happen in real-time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11004258 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that ensure successful cell division, which is crucial for preventing developmental defects and diseases like cancer. The team has identified key proteins involved in this process and is using innovative chemical inhibitors to manipulate their functions in human cells. By combining these chemical probes with advanced microscopy techniques, they aim to observe and analyze the dynamic events of cell division in real-time. This approach allows for a deeper understanding of how errors in cell division occur and how they can be prevented.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or developmental disorders related to cell division abnormalities.
Not a fit: Patients with conditions unrelated to cell division or those who are not currently experiencing any cellular dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating cancers and developmental disorders linked to cell division errors.
How similar studies have performed: Previous research has shown promise in understanding cell division mechanisms, but this approach using chemical inhibitors and advanced imaging techniques is relatively novel.
Where this research is happening
New York, United States
- Rockefeller University — New York, United States (Active)
Researchers
- Principal investigator: Kapoor, Tarun M. — Rockefeller University
- Study coordinator: Kapoor, Tarun M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.