Understanding how cells divide and separate into two new cells
Uncovering how the dynamic architecture of a layered contractile ring induces furrow ingression
This study is looking at how cells split into two, focusing on the proteins that help them do this, and it hopes to find out more about how this process works to help us understand conditions like birth defects and cancer better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10674838 on NIH RePORTER |
What this research studies
This research investigates the process of cytokinesis, which is how a single cell divides into two daughter cells. It focuses on the contractile ring made of proteins like actin and myosin that plays a crucial role in this division. By examining how these proteins are organized and function together, the research aims to uncover the mechanisms that drive cell division. This understanding could lead to insights into various conditions related to cell division, including certain congenital abnormalities and cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with congenital abnormalities or cancers that may be linked to issues in cell division.
Not a fit: Patients with conditions unrelated to cell division or those who do not have congenital abnormalities or cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for congenital defects and cancers by improving our understanding of cell division.
How similar studies have performed: Other research has shown success in understanding cell division mechanisms, making this approach promising and relevant.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Laplante, Caroline — North Carolina State University Raleigh
- Study coordinator: Laplante, Caroline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.