Understanding how cells divide and separate
Cell Division Signaling
['FUNDING_OTHER'] · VANDERBILT UNIVERSITY · NIH-11052632
This study is looking at how cells divide and what proteins help control this process, using a type of yeast to learn more about how delays in division can affect cell splitting, which is important for keeping our tissues healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY (nih funded) |
| Locations | 1 site (Nashville, UNITED STATES) |
| Trial ID | NIH-11052632 on ClinicalTrials.gov |
What this research studies
This research investigates the process of cytokinesis, which is the final step of cell division where one cell splits into two. Using the fission yeast as a model organism, the research aims to identify key proteins involved in this process and how they are regulated during the cell cycle. The study focuses on understanding the role of CK1 protein kinases in inhibiting cytokinesis when there are delays in cell division, as well as the architecture of the contractile ring that facilitates this separation. By exploring these fundamental mechanisms, the research seeks to provide insights into how cell division is precisely controlled, which is crucial for maintaining healthy tissue.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cell division abnormalities or those interested in the biological mechanisms of cell growth and development.
Not a fit: Patients with conditions unrelated to cell division or those not experiencing any cellular abnormalities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cell division, potentially informing treatments for diseases related to cell cycle dysregulation, such as cancer.
How similar studies have performed: Previous research has shown success in understanding cell division mechanisms using model organisms, indicating that this approach is promising and builds on established findings.
Where this research is happening
Nashville, UNITED STATES
- VANDERBILT UNIVERSITY — Nashville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOULD, KATHLEEN L — VANDERBILT UNIVERSITY
- Study coordinator: GOULD, KATHLEEN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.