Understanding how cells divide and move
Official title: Modeling mechanisms in cytokinesis, cell polarization and motility
Funded at Lehigh University · NIH-11011388 · Data updated 2026-11-12
This study is exploring how cells grow, split, and move by looking at the tiny structures inside them, and it's designed for anyone interested in understanding the basics of how our cells work together to keep us healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lehigh University NIH-funded |
| Lab location | 1 site (Bethlehem, United States) |
| Project start | April 1, 2020 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $526,805 |
| NIH project number | 2R35GM136372-06 |
| Project ID | NIH-11011388 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by cancers where cell division and movement play a critical role in disease progression.
✕Less likely to help
Patients with conditions unrelated to cell division or motility may not benefit from this research.
What this research studies
This research investigates the mechanisms that allow cells to divide, polarize, and move by analyzing the interactions between the cytoskeleton and cellular membranes. Using advanced computational and mathematical modeling, the project aims to link molecular interactions to cellular behaviors, focusing on specific proteins involved in cell cycle progression and cytokinesis. Collaborations with experimentalists will help validate these models through quantitative approaches, enhancing our understanding of cell biology.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cancer cell behavior and metastasis, potentially informing therapeutic strategies.
How similar studies have gone: Other research has shown promise in using computational models to understand cellular mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Lehigh University
Bethlehem, United States Active
Researchers
- Principal investigator: Vavylonis, Dimitrios — Lehigh University
- Study coordinator: Vavylonis, Dimitrios
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.