Understanding how cells divide and grow
Phosphorylation signaling in cell division
['FUNDING_OTHER'] · DARTMOUTH COLLEGE · NIH-11128763
This work explores how cells manage their growth and division, which is important for understanding diseases like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DARTMOUTH COLLEGE (nih funded) |
| Locations | 1 site (HANOVER, UNITED STATES) |
| Trial ID | NIH-11128763 on ClinicalTrials.gov |
What this research studies
Our bodies are made of cells that constantly divide and grow, a process controlled by tiny signals called phosphorylation. This project looks closely at these signals, especially those from key proteins like Aurora kinase A and B, which act like master controllers for cell division. When these signals go wrong, it can lead to serious health problems, including birth defects and cancer. By understanding how these signals normally work, we hope to learn why they sometimes fail and contribute to disease.
Who could benefit from this research
Good fit: This foundational research does not directly involve patients, but future applications may benefit individuals with cancers or other conditions linked to abnormal cell division.
Not a fit: Patients not affected by diseases related to cell division dysregulation, such as certain cancers or birth defects, would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this fundamental understanding could lead to new ways to target and treat diseases where cell division goes awry, such as cancer.
How similar studies have performed: Many previous studies have shown the critical role of phosphorylation in cell division, providing a strong foundation for this deeper exploration.
Where this research is happening
HANOVER, UNITED STATES
- DARTMOUTH COLLEGE — HANOVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GERBER, SCOTT A. — DARTMOUTH COLLEGE
- Study coordinator: GERBER, SCOTT A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.