Understanding How Cells Divide
Molecular Mechanisms of Cytokinesis
['FUNDING_R01'] · OHIO STATE UNIVERSITY · NIH-11089413
This project looks at how cells divide properly, which is important for understanding conditions like cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-11089413 on ClinicalTrials.gov |
What this research studies
Our bodies rely on cells dividing correctly for growth and health. This project focuses on the intricate process of cell division, called cytokinesis, which is often disrupted in diseases like cancer. We are using a simple model organism, fission yeast, to uncover the fundamental steps of how cells split into two. By understanding these basic mechanisms, we hope to learn more about what goes wrong when cell division is faulty. This knowledge could eventually help in developing new ways to address diseases where cell division is abnormal.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit individuals with conditions related to abnormal cell division, like cancer, in the long term.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this basic science project.
Why it matters
Potential benefit: Understanding the basic process of cell division could lead to new insights into how to control abnormal cell growth, such as in cancer.
How similar studies have performed: While the specific mechanisms are poorly understood, the general process of cytokinesis has been studied for decades, and this project builds upon existing knowledge with novel approaches.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WU, JIAN-QIU — OHIO STATE UNIVERSITY
- Study coordinator: WU, JIAN-QIU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment