Understanding how cells die and are cleared in fruit flies
The coordination of cell death and corpse clearance in Drosophila
['FUNDING_OTHER'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-11003757
This study is looking at how fruit flies handle cell death and clean up dead cells, which could help us understand similar issues in humans that might lead to diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11003757 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms of cell death and the processes involved in clearing dead cells in Drosophila, a type of fruit fly. By using advanced genetic and cell biological tools, the study aims to uncover how misregulation of these processes can lead to various human diseases. The research focuses on both non-apoptotic cell death and the removal of dead cells, particularly in tissues lacking traditional immune cells. Insights gained from this work could help in understanding similar processes in humans.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with degenerative neurological diseases or cancers related to cell death processes.
Not a fit: Patients with conditions unrelated to cell death or those not affected by the mechanisms studied in Drosophila may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases linked to cell death misregulation.
How similar studies have performed: Other research has shown success in using model organisms like Drosophila to understand cell death mechanisms, indicating that this approach is promising.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCCALL, KIMBERLY A — BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
- Study coordinator: MCCALL, KIMBERLY A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers