Understanding how cells develop and respond during early life stages
Mapping cell fate flow and feedback control on vertebrate embryonic landscapes
This study is looking at how cells grow and work together during pregnancy to understand why some babies might have developmental issues or why miscarriages happen, with the hope of finding ways to prevent these problems in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11014629 on NIH RePORTER |
What this research studies
This research investigates the complex processes that govern how cells develop and function during embryonic development. By examining the interactions between different cell types and their environments, the study aims to uncover the reasons behind developmental defects and miscarriages that occur in some pregnancies. The approach combines advanced experimental techniques with computational biology to create a comprehensive model of cell fate and behavior. This could lead to a better understanding of how to prevent or treat birth defects and developmental disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced unexplained developmental issues during pregnancy or have a family history of congenital abnormalities.
Not a fit: Patients with fully developed and healthy pregnancies or those without a history of developmental issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for birth defects and developmental disorders.
How similar studies have performed: Other research in developmental biology has shown success in understanding cell fate and developmental processes, indicating that this approach has the potential for significant findings.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Wagner, Daniel E — University of California, San Francisco
- Study coordinator: Wagner, Daniel E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.