Understanding how cells decide their fate during early development
Molecular recording to understand the determinants of cell fate transitions in early development
This study is looking at how a single cell can turn into different types of cells in mammals, using new techniques to watch this process happen in real-time, which could help us learn more about development and improve treatments in regenerative medicine.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11056874 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that determine how a single cell develops into various specialized cell types during mammalian development. By using innovative molecular recording techniques, the study aims to observe and document cellular events continuously and non-destructively. This approach allows researchers to track cell lineage and key signaling events in real-time, providing insights into the processes that guide cell fate decisions. The findings could enhance our understanding of developmental biology and have implications for regenerative medicine.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in advancements in regenerative medicine and developmental biology, particularly those affected by conditions related to cell differentiation.
Not a fit: Patients with established conditions that do not involve cellular development or differentiation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine by improving our understanding of how to manipulate cell fate for therapeutic purposes.
How similar studies have performed: Other research has shown promise with similar molecular recording techniques, indicating potential for success in this novel approach.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Choi, Junhong — Sloan-Kettering Inst Can Research
- Study coordinator: Choi, Junhong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.