Understanding how cells coordinate during reproduction
Collective dynamics in cell clusters
This study looks at how groups of cells work together during reproduction in fruit flies to help us understand the important processes that affect fertility.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project ID | NIH-10917277 on NIH RePORTER |
What this research studies
This research investigates the dynamics of cell clusters during the reproductive process using Drosophila, a model organism. It combines experimental techniques with computational modeling to explore how large cells manage cytoplasmic processes essential for fertility. The study focuses on two main areas: the hydrodynamic flows that facilitate the mixing of cellular components and the regulation of primordial germ cell numbers, which are crucial for successful reproduction. By observing these processes, the research aims to provide insights into the fundamental mechanisms of gametogenesis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in reproductive health or those experiencing fertility issues.
Not a fit: Patients who are not seeking to understand or improve reproductive health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of fertility and reproductive health, potentially leading to new treatments for infertility.
How similar studies have performed: Other research has shown success in using model organisms like Drosophila to uncover fundamental biological processes, indicating that this approach is promising.
Where this research is happening
Princeton, UNITED STATES
- Princeton University — Princeton, United States (Active)
Researchers
- Principal investigator: Shvartsman, Stanislav Y. — Princeton University
- Study coordinator: Shvartsman, Stanislav Y.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.