Understanding how cells control their growth and division
Molecular Mechanisms of Cell Cycle Dependent Gene Expression
This study is looking at how cells decide when to divide, which is important for understanding cancer, and it aims to find new ways to improve treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Santa Cruz NIH-funded |
| Lab location | 1 site (Santa Cruz, United States) |
| Project ID | NIH-10928125 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that regulate the cell cycle, focusing on the proteins and pathways that determine when a cell should divide. By studying transcription factors and their interactions with chromatin, the research aims to uncover new insights into how gene expression is controlled during cell division. The approach combines structural biology with cell-based assays to explore these complex interactions. The findings could lead to the development of improved therapies for cancer by addressing the limitations of current treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancers that are driven by dysregulation of the cell cycle.
Not a fit: Patients with non-cancerous conditions or those whose cancers are not related to cell cycle dysregulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer therapies by providing a deeper understanding of cell cycle regulation.
How similar studies have performed: Previous research has shown success in targeting cell cycle mechanisms for cancer treatment, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Santa Cruz, United States
- University of California Santa Cruz — Santa Cruz, United States (Active)
Researchers
- Principal investigator: Rubin, Seth Michael — University of California Santa Cruz
- Study coordinator: Rubin, Seth Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.