Understanding how cells control their growth and division
Official title: Regulation of Key Cell Cycle Events
Funded at Univ of Massachusetts Med Sch Worcester · NIH-10914767 · Data updated 2026-11-12
This study looks at how tiny cells decide when to grow and divide, using a simple organism called fission yeast, to help us understand what goes wrong in diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $800,149 |
| NIH project number | 5R35GM148359-02 |
| Project ID | NIH-10914767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by cancers or conditions that involve abnormal cell growth and size regulation.
✕Less likely to help
Patients with stable, non-cancerous conditions that do not involve issues with cell growth or division may not benefit from this research.
What this research studies
This research investigates how cells make decisions about when to divide and how to manage their size, which is crucial for their proper function. By studying fission yeast, a simple and well-understood organism, the researchers aim to uncover the mechanisms that regulate cell size and DNA replication timing. This could provide insights into how these processes go awry in diseases like cancer. The research employs experimental techniques to analyze the expression of specific proteins that influence cell division and size.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating cancers and other diseases related to cell growth and size regulation.
How similar studies have gone: Previous research has shown promising results in understanding cell cycle regulation in simpler organisms, suggesting potential for breakthroughs in more complex systems.
Where this research is happening
-
Univ of Massachusetts Med Sch Worcester
Worcester, United States Active
Researchers
- Principal investigator: Rhind, Nicholas R — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Rhind, Nicholas R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.