Understanding how cells communicate in head and neck cancer progression.
Elucidating mechanisms of cellular communication critical for head and neck cancer progression and metastasis.
This study is looking at how different cells in head and neck tumors work together and affect cancer growth, with the goal of finding better treatments for patients with head and neck cancer.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11009922 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between different cell types within head and neck tumors, particularly focusing on how these interactions contribute to cancer progression and metastasis. By examining the molecular signaling pathways and the role of immune cells, such as neutrophils and B cells, the study aims to uncover mechanisms that drive tumor growth and resistance to treatment. The research utilizes mouse models to explore these cellular dynamics, which could lead to the development of targeted therapies for patients with head and neck squamous cell carcinoma.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck squamous cell carcinoma, particularly those with aggressive disease or treatment-resistant cases.
Not a fit: Patients with head and neck cancer caused by HPV or those with non-squamous cell carcinoma types may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies that improve survival rates and treatment options for patients with head and neck cancer.
How similar studies have performed: Previous research has shown promising results in understanding cellular interactions in cancer, suggesting that this approach could yield valuable insights and advancements in treatment.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Kroehling, Lina — Boston University (Charles River Campus)
- Study coordinator: Kroehling, Lina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.