Understanding how cells communicate in COPD
Local cellular communication networks in COPD endotypes
['FUNDING_R21'] · YALE UNIVERSITY · NIH-11067867
This study is looking at how cells in the lungs of people with Chronic Obstructive Pulmonary Disease (COPD) communicate with each other, hoping to find new ways to treat the condition by analyzing lung tissue samples from participants.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11067867 on ClinicalTrials.gov |
What this research studies
This research investigates the communication networks between cells in patients with Chronic Obstructive Pulmonary Disease (COPD). By utilizing advanced techniques like single-cell sequencing and spatial transcriptomics, the study aims to identify abnormal cell populations and their interactions within the lung tissue. The goal is to uncover the mechanisms behind the diverse manifestations of COPD, which may lead to new therapeutic strategies tailored to individual patients. Participants may contribute to a better understanding of their condition through the analysis of their lung tissue samples.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Chronic Obstructive Pulmonary Disease (COPD), particularly those with varying clinical presentations.
Not a fit: Patients without a diagnosis of COPD or those with other unrelated respiratory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment options for patients with COPD, improving their quality of life.
How similar studies have performed: Previous research has shown promise in understanding cell communication in other diseases, suggesting that this approach could yield valuable insights in COPD as well.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SAULER, MAOR — YALE UNIVERSITY
- Study coordinator: SAULER, MAOR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.