Understanding how cells communicate and respond to their environment
Mathematical modeling of cellular signaling systems
This study is exploring how cells pick up and react to signals from their environment, like hormones and nutrients, to better understand how they work, which could help us learn more about health and diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10892028 on NIH RePORTER |
What this research studies
This research investigates the intricate mechanisms that control how cells sense and respond to various environmental signals. By combining mathematical modeling with experimental techniques at the single-cell level, the project aims to uncover how cells process information from their surroundings, such as hormones and nutrients. The focus is on understanding the dynamics of intracellular signaling pathways and how they coordinate cellular responses, including changes in shape and movement. This research could lead to insights into fundamental cellular processes that are crucial for health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular signaling dysfunction, such as certain cancers or cardiac diseases.
Not a fit: Patients with conditions unrelated to cellular signaling or those who do not have a cellular signaling disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular behavior, potentially leading to new treatments for diseases like cancer and cardiac disorders.
How similar studies have performed: Other research has shown success in using mathematical modeling to understand cellular processes, indicating that this approach has potential for significant findings.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Elston, Timothy C — Univ of North Carolina Chapel Hill
- Study coordinator: Elston, Timothy C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.