Understanding how cells communicate and move during tissue development
Mechanosensitive mechanisms regulating cellular coordination during tissue morphogenesis and patterning
This study is looking at how cells in our bodies feel and respond to physical forces, which helps them work together and move properly during tissue development, and it's important for keeping our organs healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10843105 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which cells sense mechanical signals and coordinate their movements during the development of tissues. It focuses on the role of specific proteins that respond to mechanical forces, which are crucial for cell communication and movement. By studying these processes, the research aims to uncover how cells interact and function together in healthy tissues, which is important for maintaining balance and proper organ function. The approach includes examining how these mechanosensitive proteins influence the transfer of electrical signals and other important cellular messages.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cardiac arrhythmias or other diseases associated with compromised mechanosensation.
Not a fit: Patients with stable, non-mechanosensitive conditions unrelated to cellular communication or movement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into treating conditions like atrial fibrillation and other diseases linked to cell communication failures.
How similar studies have performed: Previous research has shown promising results in understanding mechanosensitive mechanisms, indicating potential for significant advancements in this area.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Stratman, Amber Nicole — Washington University
- Study coordinator: Stratman, Amber Nicole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.