Understanding how cells communicate and function in health and disease
Official title: Chemical Approaches for Interrogating Fundamental Biomedical Processes
Funded at University of Virginia · NIH-10900559 · Data updated 2026-11-12
This study is exploring how cells talk to each other and respond to different signals, using special tools to watch and change these processes in real-time, which could help us find new ways to treat diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $390,681 |
| NIH project number | 5R35GM148221-02 |
| Project ID | NIH-10900559 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to cellular signaling abnormalities, such as certain cancers or metabolic disorders.
✕Less likely to help
Patients with conditions unrelated to cellular signaling or those who do not have a cellular communication disorder may not benefit from this research.
What this research studies
This research focuses on the intricate processes of cellular communication and signaling, which are essential for normal cell function. By developing advanced fluorescent probes and protein-based systems, the researchers aim to monitor and manipulate these signaling pathways in real-time. This approach will help illuminate how cells interact and respond to various stimuli, particularly in the context of diseases. The ultimate goal is to gain a deeper understanding of cellular processes that could lead to new therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating diseases linked to cellular signaling dysfunction.
How similar studies have gone: Previous research has shown success in using fluorescent probes and protein-based systems to study cellular processes, indicating a promising approach.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Stains, Cliff I — University of Virginia
- Study coordinator: Stains, Cliff I
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.