Understanding how cells communicate and divide during reproduction
Noncanonical regulatory mechanisms in cell biology
['FUNDING_OTHER'] · YALE UNIVERSITY · NIH-11064078
This study is looking at how reproductive cells divide and communicate, especially when they don't separate properly, which can affect fertility and lead to health problems; the goal is to find out why this happens so we can develop better treatments for people facing these issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11064078 on ClinicalTrials.gov |
What this research studies
This research investigates the complex processes of cell division and communication in reproductive cells, focusing on how certain cells fail to separate properly during division. By studying the genetic and molecular mechanisms involved, the research aims to uncover the reasons behind incomplete cell division in germline cells, which can lead to issues in fertility and certain diseases. The approach includes advanced imaging techniques and molecular biology methods to identify key proteins and their roles in these processes. Patients may benefit from insights that could lead to new treatments for reproductive health issues.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals experiencing fertility challenges or those with reproductive health disorders.
Not a fit: Patients with non-reproductive health issues or those outside the age range of 21+ years may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for improving reproductive health and addressing fertility issues.
How similar studies have performed: Previous research has shown success in understanding cell division and communication, but this specific approach to studying germline cells is relatively novel.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COOLEY, LYNN — YALE UNIVERSITY
- Study coordinator: COOLEY, LYNN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.