Understanding how cells close gaps during wound healing and tissue development

Biophysics and Cell Biology of Meso-scale Gap Closure

NIH-funded research University of Massachusetts Amherst · NIH-10939597

This study looks at how cells work together to heal wounds and keep tissues healthy, focusing on how they move and change to close gaps, which could help us learn more about improving healing and tissue repair.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Amherst NIH-funded
Lab location1 site (Hadley, United States)
Project IDNIH-10939597 on NIH RePORTER

What this research studies

This research investigates the mechanisms by which cells close gaps in tissues, a crucial process for wound healing and maintaining healthy tissue during development. It focuses on how certain cellular behaviors, such as coordinated movement and changes in tissue properties, contribute to this process. By studying the roles of specific proteins and cellular structures, the research aims to uncover new insights into how cells interact with their environment and each other during gap closure. This could lead to a better understanding of tissue repair and regeneration.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals with conditions that impair wound healing or tissue regeneration.

Not a fit: Patients with stable, non-healing wounds or those not experiencing tissue repair issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could improve treatments for wounds and tissue injuries, enhancing healing processes.

How similar studies have performed: Other research has shown promising results in understanding cellular mechanisms in wound healing, suggesting that this approach could yield valuable insights.

Where this research is happening

Hadley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.