Understanding how cells close gaps during wound healing and tissue development
Official title: Biophysics and Cell Biology of Meso-scale Gap Closure
Funded at University of Massachusetts Amherst · NIH-10939597 · Data updated 2026-11-12
This study looks at how cells work together to heal wounds and keep tissues healthy, focusing on how they move and change to close gaps, which could help us learn more about improving healing and tissue repair.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Amherst NIH-funded |
| Lab location | 1 site (Hadley, United States) |
| Project start | July 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $389,211 |
| NIH project number | 1R35GM155279-01 |
| Project ID | NIH-10939597 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals with conditions that impair wound healing or tissue regeneration.
✕Less likely to help
Patients with stable, non-healing wounds or those not experiencing tissue repair issues may not benefit from this research.
What this research studies
This research investigates the mechanisms by which cells close gaps in tissues, a crucial process for wound healing and maintaining healthy tissue during development. It focuses on how certain cellular behaviors, such as coordinated movement and changes in tissue properties, contribute to this process. By studying the roles of specific proteins and cellular structures, the research aims to uncover new insights into how cells interact with their environment and each other during gap closure. This could lead to a better understanding of tissue repair and regeneration.
Why it matters
Potential benefit: If successful, this research could improve treatments for wounds and tissue injuries, enhancing healing processes.
How similar studies have gone: Other research has shown promising results in understanding cellular mechanisms in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Massachusetts Amherst
Hadley, United States Active
Researchers
- Principal investigator: Sun, Yubing — University of Massachusetts Amherst
- Study coordinator: Sun, Yubing
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.