Understanding how cells change shape and move during development and healing
Control and Implementation of a Morphogenetic Program
['FUNDING_R01'] · NEW YORK UNIVERSITY · NIH-10814884
This study looks at how cells change shape and move, which is important for things like healing wounds and understanding cancer, and it uses tiny worms to learn more about the timing and control of these processes, hoping to find new ways to help with birth defects and cancer treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10814884 on ClinicalTrials.gov |
What this research studies
This research investigates the process of cellular morphogenesis, which is crucial for animal development, wound healing, and cancer progression. It focuses on how cells change shape, migrate, and fuse, driven by specific molecules known as effectors and regulators. The study aims to uncover the timing mechanisms of these morphogenetic events and how they are controlled by long non-coding RNAs and transcription factors, using a model organism, C. elegans. By exploring these cellular processes, the research seeks to provide insights that could lead to advancements in treating conditions related to birth defects and cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with congenital abnormalities or cancers that may benefit from insights into cellular morphogenesis.
Not a fit: Patients with conditions unrelated to cellular morphogenesis or those who are not adults may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating birth defects and cancers by improving our understanding of cellular behavior.
How similar studies have performed: Previous research has shown promising results in understanding cellular morphogenesis, indicating that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FITCH, DAVID H. A. — NEW YORK UNIVERSITY
- Study coordinator: FITCH, DAVID H. A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.