Understanding how cells change shape and move
Official title: Dynamic pattern formation in the cell cortex
Funded at University of Wisconsin-Madison · NIH-11010994 · Data updated 2026-11-12
This study is looking at how the outer layer of cells, which helps them respond to signals and change shape, works by examining special proteins that create patterns, and it's for anyone interested in understanding how cells divide, move, and heal.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | February 15, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $414,285 |
| NIH project number | 1R35GM156206-01 |
| Project ID | NIH-11010994 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to abnormal cell proliferation or metastasis.
✕Less likely to help
Patients with stable, non-progressive conditions that do not involve cell movement or proliferation may not benefit from this research.
What this research studies
This research investigates the cell cortex, the outer layer of cells that plays a crucial role in how cells respond to signals and change shape. By studying the dynamic patterns formed by proteins called Rho GTPases, the research aims to uncover how these patterns influence important processes like cell division, movement, and repair. The approach involves using advanced tools to observe and analyze these patterns in both vertebrate and invertebrate cells, providing insights into their biological functions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases related to cell growth and movement, such as cancer.
How similar studies have gone: Previous research has shown promising results in understanding cell behavior through similar approaches, indicating potential for significant advancements.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Bement, William — University of Wisconsin-Madison
- Study coordinator: Bement, William
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.