Understanding how cells change shape and move
Dynamic pattern formation in the cell cortex
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11010994
This study is looking at how the outer layer of cells, which helps them respond to signals and change shape, works by examining special proteins that create patterns, and it's for anyone interested in understanding how cells divide, move, and heal.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11010994 on ClinicalTrials.gov |
What this research studies
This research investigates the cell cortex, the outer layer of cells that plays a crucial role in how cells respond to signals and change shape. By studying the dynamic patterns formed by proteins called Rho GTPases, the research aims to uncover how these patterns influence important processes like cell division, movement, and repair. The approach involves using advanced tools to observe and analyze these patterns in both vertebrate and invertebrate cells, providing insights into their biological functions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to abnormal cell proliferation or metastasis.
Not a fit: Patients with stable, non-progressive conditions that do not involve cell movement or proliferation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases related to cell growth and movement, such as cancer.
How similar studies have performed: Previous research has shown promising results in understanding cell behavior through similar approaches, indicating potential for significant advancements.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEMENT, WILLIAM — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: BEMENT, WILLIAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: cancer metastasis