Understanding how cells change and grow
Investigating the Regulatory Roles of Histone Chaperones in Cellular Plasticity
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-11139497
This research explores how special proteins called histone chaperones help control how our cells develop and change.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded) |
| Locations | 1 site (RIVERSIDE, UNITED STATES) |
| Trial ID | NIH-11139497 on ClinicalTrials.gov |
What this research studies
Our bodies are made of many different types of cells, and each cell type has a specific job. This project looks at how certain proteins, called histone chaperones, act like guides to organize the cell's genetic material, called chromatin. These chaperones are important for cells to grow and multiply correctly, and they also help determine what a cell will become. We want to learn more about how these chaperones influence a cell's ability to change its identity, which is called cellular plasticity.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation at this stage.
Not a fit: Patients seeking immediate new treatments or clinical trial opportunities would not find direct benefit from this basic science project.
Why it matters
Potential benefit: Understanding these basic cellular processes could eventually lead to new ways to address conditions involving uncontrolled cell growth or problems with cell development.
How similar studies have performed: While the specific mechanisms are still being uncovered, other basic science efforts have shown the importance of chromatin regulation in cell fate and disease.
Where this research is happening
RIVERSIDE, UNITED STATES
- UNIVERSITY OF CALIFORNIA RIVERSIDE — RIVERSIDE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHELOUFI, SIHEM — UNIVERSITY OF CALIFORNIA RIVERSIDE
- Study coordinator: CHELOUFI, SIHEM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.