Understanding how cell surface receptors interact and function
Official title: Resolving the interaction network of cell surface receptors
Funded at Texas Tech University · NIH-10765486 · Data updated 2026-11-12
This study is looking at how certain cell receptors communicate with each other, which is important for understanding diseases like cancer, asthma, and arthritis, and it hopes to help create better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $366,935 |
| NIH project number | 1R35GM152126-01 |
| Project ID | NIH-10765486 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from conditions like cancer, asthma, or arthritis, where cell signaling plays a critical role.
✕Less likely to help
Patients with conditions unrelated to cell surface receptor signaling may not receive any benefit from this research.
What this research studies
This research investigates the interactions of cell surface receptors, which are crucial for cell signaling and communication. By using advanced live cell methodologies, the study aims to quantify how these receptors, particularly receptor tyrosine kinases and G protein-coupled receptors, interact with each other and respond to different ligands in their natural environment. This could lead to a better understanding of diseases like cancer, asthma, and arthritis, where these receptors play significant roles. Patients may benefit from insights that could inform the development of targeted therapies and improve treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for various diseases, improving treatment options for patients.
How similar studies have gone: Previous research has shown success in understanding receptor interactions and their implications for disease treatment, indicating that this approach is promising.
Where this research is happening
-
Texas Tech University
Lubbock, United States Active
Researchers
- Principal investigator: Smith, Adam W. — Texas Tech University
- Study coordinator: Smith, Adam W.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.