Understanding how cell signals control body functions
Regulation of Adenylyl Cyclase Signaling Pathways
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-11141780
This work explores how a key signaling pathway in our cells, called adenylyl cyclase, helps control many important body functions like learning, heart health, and managing pain or anxiety.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11141780 on ClinicalTrials.gov |
What this research studies
Our bodies rely on tiny signals within cells to manage everything from memory to heartbeats. This project focuses on a crucial signaling molecule called adenylyl cyclase (AC) and its product, cyclic AMP, which act like messengers in nearly every tissue and organ. We are learning how these messengers are controlled by other proteins and how they create specific responses in cells. Understanding these basic mechanisms could help us develop better treatments for conditions like heart disease, pain, and anxiety, as many current medications already target these pathways.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future clinical applications could benefit individuals with conditions related to learning, memory, heart function, pain, stress, or anxiety.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not find direct benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how our bodies function and potentially inspire new and more effective treatments for a wide range of diseases and conditions.
How similar studies have performed: Research into adenylyl cyclase and cyclic AMP signaling has been ongoing for decades, with many existing medications targeting these pathways, indicating a strong foundation for this approach.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DESSAUER, CARMEN W. — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: DESSAUER, CARMEN W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.