Understanding how cell processes affect aging and longevity
Official title: Pexophagy regulation in live animals and its role in aging and longevity
Funded at Louisiana State Univ A&m Col Baton Rouge · NIH-10988263 · Data updated 2026-11-12
This study looks at how a process called pexophagy, which helps cells break down certain structures, changes as we get older, using tiny worms to learn more about how this affects our health and aging, with the hope of finding ways to help people age healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ A&m Col Baton Rouge NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $268,081 |
| NIH project number | 5R01AG079970-03 |
| Project ID | NIH-10988263 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are interested in the biological aspects of aging.
✕Less likely to help
Patients under the age of 65 or those with acute health conditions unrelated to aging may not receive benefits from this research.
What this research studies
This research investigates the role of pexophagy, a process where cells degrade peroxisomes, in the aging process. By studying the nematode Caenorhabditis elegans, the researchers aim to uncover how the rate of pexophagy changes with age and its implications for health and longevity. The study focuses on understanding the cellular mechanisms that contribute to physiological decline and age-related diseases, potentially leading to strategies that promote healthier aging. Patients may benefit from insights gained about cellular health and longevity.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for promoting longer and healthier lives in older adults.
How similar studies have gone: While the specific focus on pexophagy in aging is relatively novel, related research has shown promising results in understanding cellular processes and their impact on longevity.
Where this research is happening
-
Louisiana State Univ A&m Col Baton Rouge
Baton Rouge, United States Active
Researchers
- Principal investigator: Bohnert, Kenneth Adam — Louisiana State Univ A&m Col Baton Rouge
- Study coordinator: Bohnert, Kenneth Adam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.