Understanding how cell movement is controlled in cancer
Kinase Control of Synergistic Cell Migration Mechanics
This study is looking at how certain proteins help cancer cells move around, which is important for understanding how cancer spreads, and the goal is to find better ways to stop this movement to help patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11053532 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that regulate cell migration, particularly in the context of cancer metastasis. By focusing on the protein kinase ERK, the study aims to uncover how fluctuations in cellular forces influence the movement of cancer cells. The approach involves analyzing the signaling pathways that dictate the behavior of cells during migration, which could lead to improved treatment strategies for cancer. Patients may benefit from insights gained about how to inhibit harmful cell movement associated with cancer spread.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancer, particularly those whose tumors exhibit high levels of cell migration.
Not a fit: Patients with non-cancerous conditions or those whose cancer does not involve significant cell migration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cancer metastasis, improving patient outcomes.
How similar studies have performed: Other research has shown promising results in understanding cell migration mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Mendoza, Michelle Christine — University of Utah
- Study coordinator: Mendoza, Michelle Christine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.