Understanding how cell membranes function and interact
Mechanisms in Membrane Dynamics
['FUNDING_OTHER'] · YALE UNIVERSITY · NIH-11051216
This study is looking at how cell membranes work and communicate with each other, especially focusing on certain proteins that help move fats around, which could help us understand and improve conditions like Alzheimer's disease.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11051216 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which cell membranes maintain their structure and facilitate communication between different organelles within cells. It focuses on the role of proteins that mediate lipid transfer at contact sites where organelles are closely positioned. By identifying and characterizing these proteins, the research aims to uncover the processes that regulate lipid composition and membrane dynamics, which are crucial for cell health and function. Patients with conditions like Alzheimer's disease may benefit from insights gained about cellular dysfunctions related to membrane dynamics.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with non-neurological conditions or those without any cognitive impairments may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease and other related conditions.
How similar studies have performed: Other research has shown promising results in understanding membrane dynamics and their implications in neurodegenerative diseases, suggesting that this approach has potential for significant findings.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REINISCH, KARIN M — YALE UNIVERSITY
- Study coordinator: REINISCH, KARIN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease