Understanding how cell cycle checkpoints work in tiny worms.
Cell cycle checkpoint control in C. elegans
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA SANTA CRUZ · NIH-11094876
This study looks at how tiny worms make sure their cells divide properly, which is important for understanding problems like cancer and infertility in humans.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA CRUZ (nih funded) |
| Locations | 1 site (SANTA CRUZ, UNITED STATES) |
| Trial ID | NIH-11094876 on ClinicalTrials.gov |
What this research studies
This research investigates the role of cell cycle checkpoints in the tiny worm C. elegans, focusing on how these checkpoints ensure that cells divide correctly and maintain the right number of chromosomes. By examining how these checkpoints function in different cellular contexts, the research aims to uncover mechanisms that could explain issues like cancer and infertility in multicellular organisms. The study employs advanced techniques to analyze checkpoint proteins and their behavior in various cell types, providing insights into their regulation and function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by conditions related to chromosomal abnormalities, including cancer patients and those experiencing infertility.
Not a fit: Patients with conditions unrelated to chromosomal abnormalities or those not experiencing issues with cell division may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for conditions related to chromosomal abnormalities, such as cancer and infertility.
How similar studies have performed: Other research has shown success in understanding cell cycle checkpoints in single cells, but this approach in multicellular organisms like C. elegans is relatively novel.
Where this research is happening
SANTA CRUZ, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA CRUZ — SANTA CRUZ, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BHALLA, NEEDHI — UNIVERSITY OF CALIFORNIA SANTA CRUZ
- Study coordinator: BHALLA, NEEDHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers