Understanding How Cell Control Centers Work
Molecular, material, and structural design principles of centrosomes
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11139425
This research helps us understand how tiny parts of our cells, called centrosomes, control cell division and development, which is important for preventing diseases like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11139425 on ClinicalTrials.gov |
What this research studies
Our cells have special control centers called centrosomes that help them divide properly and develop correctly. When these centrosomes don't work right, it can lead to serious health problems, including certain cancers and developmental disorders. This project aims to uncover the basic rules that determine how these centrosomes are built and how they function. By understanding their structure and properties, we hope to learn why they sometimes malfunction.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit those affected by conditions linked to cell division problems, like cancer or developmental disorders.
Not a fit: Patients whose conditions are unrelated to cell division or centrosome function would likely not see direct benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to understand and potentially treat diseases caused by faulty cell division, such as cancers and certain developmental disorders.
How similar studies have performed: This project uses newly developed, innovative techniques to explore fundamental aspects of centrosome biology, making its approach quite novel.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WOODRUFF, JEFFREY B — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: WOODRUFF, JEFFREY B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Disease, Disorder