Understanding how cell connections and actin filaments work together
A Molecular Toolkit for Controlling and Probing Cell Junction-Actin Interactions
This study is looking at how tiny structures in our cells work together to keep our tissues healthy, and it aims to help us understand how these processes might be linked to diseases like cancer, which could lead to better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project ID | NIH-11089339 on NIH RePORTER |
What this research studies
This research focuses on the interactions between cell junctions and actin filaments, which are crucial for maintaining the structure and function of tissues. By developing a molecular toolkit, the researchers aim to control and investigate these interactions in detail. This approach will help clarify how actin contributes to the formation, maintenance, and signaling of cell junctions, which are vital for tissue integrity and communication. Patients may benefit from insights gained about how these processes are involved in various diseases, including cancers.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to cell adhesion and junction integrity, particularly those with cancer.
Not a fit: Patients with conditions unrelated to cell junctions or actin filament dysfunction may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases related to cell junction dysfunction, such as certain cancers.
How similar studies have performed: Other research has shown success in understanding cell junctions and actin interactions, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Austin, United States
- University of Texas at Austin — Austin, United States (Active)
Researchers
- Principal investigator: Belardi, Brian — University of Texas at Austin
- Study coordinator: Belardi, Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.