Understanding how CBD affects stress and nicotine withdrawal for smokers

Psychopharmacological effects of cannabidiol on responses to stress and nicotine withdrawal

['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-11081625

This research looks at how cannabidiol, or CBD, might help people manage stress and withdrawal symptoms when they try to stop smoking.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-11081625 on ClinicalTrials.gov

What this research studies

Many people who try to quit smoking find it difficult because of stress and uncomfortable withdrawal symptoms. This project explores whether cannabidiol (CBD), a compound from cannabis, could help reduce these stress-related changes in the body and mind. Researchers aim to understand how CBD affects your body's stress response and mood, especially during the challenging period of nicotine withdrawal. The ultimate goal is to learn more about how CBD works and if it could be a useful tool to support individuals trying to quit tobacco.

Who could benefit from this research

Good fit: Ideal candidates for future related studies might be adult smokers who are trying to quit and experience significant stress or withdrawal symptoms.

Not a fit: Patients who do not smoke or are not attempting to quit tobacco would likely not receive direct benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new strategies or treatments to help people overcome nicotine addiction by better managing stress and withdrawal symptoms.

How similar studies have performed: While previous work has shown how stress and hormones affect tobacco withdrawal, this specific exploration of CBD's role in managing these symptoms is relatively new.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.