NIH-funded research R01 grant

Understanding how caregiving for a spouse with Alzheimer's affects health and well-being

Official title: Individual differences in dementia spousal caregiver burden: A biobehavioral approach

Funded at Rice University · NIH-10617191 · Data updated 2026-11-12

This study looks at how taking care of a spouse with Alzheimer's affects the health and emotions of the caregiver, focusing on how different personalities and relationships play a role, so we can find ways to better support those caregivers who might be struggling.

More Dementia research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRice University
NIH-funded
Lab location1 site (Houston, United States)
Project startJune 15, 2019
Project endMarch 31, 2026
Funding year2023
Award (this year)$745,658
NIH project number5R01AG062690-05
Project IDNIH-10617191 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are spousal caregivers of individuals diagnosed with Alzheimer's Disease.

Less likely to help

Patients who are not caregivers or who are not involved in a spousal relationship with someone diagnosed with Alzheimer's Disease may not benefit from this research.

What this research studies

This research investigates the impact of caregiving for a spouse with Alzheimer's Disease on the caregiver's health and emotional well-being. It focuses on how individual differences, such as personality traits and relationship dynamics, influence the caregiver's experience and biological health markers. By examining these factors, the study aims to identify which caregivers are at greater risk for health issues due to the stress of caregiving. The findings could lead to tailored interventions to support caregivers more effectively.

Why it matters

Potential benefit: If successful, this research could provide insights that lead to improved support and interventions for spousal caregivers of individuals with Alzheimer's Disease.

How similar studies have gone: While there has been research on caregiver stress, this study's specific focus on individual differences and biological health markers in spousal caregivers is relatively novel.

Where this research is happening

  • Rice University
    Houston, United States
    Active

Researchers

  • Principal investigator: Fagundes, Christopher Paul — Rice University
  • Study coordinator: Fagundes, Christopher Paul

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.