Understanding how cannabis affects adolescents and their reactions to cannabis cues.

Sensitivity to Cannabis Effects and Cue Reactivity as Markers of a Developing Disorder in Adolescents

NIH-funded research Brown University · NIH-11037975

This study is looking at how using cannabis as a teenager might change the way your brain responds to rewards, which could lead to problems with cannabis use later on, and it involves 224 teens aged 13 to 16 who have used cannabis recently, tracking their experiences and feelings about it over three years using their smartphones.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrown University NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11037975 on NIH RePORTER

What this research studies

This research investigates how cannabis use during adolescence can lead to changes in the brain's reward systems, potentially resulting in cannabis use disorder (CUD). By using smartphone technology to gather real-time data on adolescents' experiences with cannabis, the study aims to track changes in their reactions to cannabis effects and cues over time. The research will involve 224 adolescents aged 13 to 16 who have used cannabis in the past month, with assessments conducted annually over three years to monitor their development and symptoms related to cannabis use.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 13 to 16 who have used cannabis in the past month.

Not a fit: Patients who do not use cannabis or are outside the age range of 13 to 16 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cannabis use disorder in adolescents.

How similar studies have performed: Previous research has shown that monitoring cannabis use and its effects in real-time can provide valuable insights into substance use disorders, indicating potential for success in this approach.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.