Understanding how cannabis affects adolescents and their reactions to cannabis cues.
Official title: Sensitivity to Cannabis Effects and Cue Reactivity as Markers of a Developing Disorder in Adolescents
Funded at Brown University · NIH-11037975 · Data updated 2026-11-12
This study is looking at how using cannabis as a teenager might change the way your brain responds to rewards, which could lead to problems with cannabis use later on, and it involves 224 teens aged 13 to 16 who have used cannabis recently, tracking their experiences and feelings about it over three years using their smartphones.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | May 15, 2023 |
| Project end | February 28, 2028 |
| Funding year | 2025 |
| Award (this year) | $631,660 |
| NIH project number | 5R01DA055600-03 |
| Project ID | NIH-11037975 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 13 to 16 who have used cannabis in the past month.
✕Less likely to help
Patients who do not use cannabis or are outside the age range of 13 to 16 may not benefit from this research.
What this research studies
This research investigates how cannabis use during adolescence can lead to changes in the brain's reward systems, potentially resulting in cannabis use disorder (CUD). By using smartphone technology to gather real-time data on adolescents' experiences with cannabis, the study aims to track changes in their reactions to cannabis effects and cues over time. The research will involve 224 adolescents aged 13 to 16 who have used cannabis in the past month, with assessments conducted annually over three years to monitor their development and symptoms related to cannabis use.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cannabis use disorder in adolescents.
How similar studies have gone: Previous research has shown that monitoring cannabis use and its effects in real-time can provide valuable insights into substance use disorders, indicating potential for success in this approach.
Where this research is happening
-
Brown University
Providence, United States Active
Researchers
- Principal investigator: Treloar Padovano, Hayley — Brown University
- Study coordinator: Treloar Padovano, Hayley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.