Understanding how cannabinoid receptors work for better medicines
Project 2 - Molecular pharmacology of cannabinoid receptor probes
['FUNDING_P01'] · NORTHEASTERN UNIVERSITY · NIH-11128512
This research explores how cannabinoid receptors in the body signal to find new ways to develop safer and more effective medicines.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHEASTERN UNIVERSITY (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11128512 on ClinicalTrials.gov |
What this research studies
We are looking closely at how cannabinoid receptors, like CB1 and CB2, send signals in the body. By understanding these signals better, we hope to find new ways to create medicines that offer the benefits of cannabinoids without unwanted side effects. This involves studying new compounds that can specifically target these receptors and influence their signaling pathways. The goal is to identify which signaling pathways are most important for treatment and which ones cause problems.
Who could benefit from this research
Good fit: Patients interested in future treatments for conditions that might benefit from cannabinoid therapies could potentially benefit from the outcomes of this foundational research.
Not a fit: Patients seeking immediate treatment options or direct participation in a clinical trial would not directly benefit from this early-stage laboratory research.
Why it matters
Potential benefit: If successful, this work could lead to the development of new cannabinoid-based medicines that are more effective and have fewer side effects for various conditions.
How similar studies have performed: This research explores newer concepts like functional selectivity and allosteric modulation, representing alternative strategies to traditional approaches, building on existing knowledge but with novel angles.
Where this research is happening
BOSTON, UNITED STATES
- NORTHEASTERN UNIVERSITY — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOHN, LAURA M. — NORTHEASTERN UNIVERSITY
- Study coordinator: BOHN, LAURA M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.