Understanding how Candida auris grows on the skin
Official title: Mechanisms of Candida auris Colonization in the Skin
Funded at Purdue University · NIH-10910133 · Data updated 2026-11-12
This study is looking at how a fungus called Candida auris can grow on our skin and how the good bacteria on our skin can help stop it, with the goal of finding ways to prevent infections and keep people safe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project start | August 18, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $599,355 |
| NIH project number | 5R01AI177604-02 |
| Project ID | NIH-10910133 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include hospitalized patients and nursing home residents who are at risk of Candida auris colonization and infection.
✕Less likely to help
Patients who are not at risk of Candida auris colonization, such as those with healthy skin microbiota and no underlying health conditions, may not benefit from this research.
What this research studies
This research investigates the mechanisms by which the fungus Candida auris colonizes the skin, which is crucial for preventing its spread and associated infections. The study focuses on the role of skin microbiota in inhibiting the growth of this multi-drug resistant pathogen. Researchers will explore both the direct effects of skin microbiota on Candida auris and the host-mediated mechanisms that regulate its colonization. By identifying these factors, the research aims to develop strategies to control outbreaks and reduce the risk of severe infections.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for preventing Candida auris infections, particularly in vulnerable populations.
How similar studies have gone: Previous research has shown that understanding the role of microbiota in pathogen colonization can lead to successful interventions, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Purdue University
West Lafayette, United States Active
Researchers
- Principal investigator: Thangamani, Shankar — Purdue University
- Study coordinator: Thangamani, Shankar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.