Understanding how Candida auris colonizes the skin
Official title: Genetic circuitry governing skin colonization of Candida auris
Funded at University of Michigan at Ann Arbor · NIH-10820625 · Data updated 2026-11-12
This study is looking at how certain genes in the fungus Candida auris help it stick to human skin, which is important for spreading infections in hospitals, and the findings could help us find better ways to prevent these infections.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | August 1, 2024 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $79,806 |
| NIH project number | 1F32AI181164-01 |
| Project ID | NIH-10820625 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are hospitalized or have compromised immune systems, as they are at higher risk for Candida auris infections.
✕Less likely to help
Patients who are healthy and not at risk for fungal infections may not benefit from this research.
What this research studies
This research investigates the genetic factors that enable the fungus Candida auris to colonize human skin, which is crucial for its transmission in healthcare settings. By examining the specific genes and proteins involved in skin adhesion, the study aims to uncover the mechanisms that make this pathogen particularly virulent. The research utilizes advanced molecular biology techniques to analyze different strains of C. auris and their ability to adhere to skin tissues. This knowledge could lead to better prevention strategies against infections caused by this dangerous fungus.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for preventing Candida auris infections, particularly in hospital settings.
How similar studies have gone: While research on Candida auris is still emerging, studies on related fungal pathogens like Candida albicans have shown success in understanding adhesion mechanisms.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Zhao, Guolei — University of Michigan at Ann Arbor
- Study coordinator: Zhao, Guolei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.