Understanding how cancer spreads and affects the body
Systemic regulation of metastasis
This study looks at how tumors communicate with the rest of the body to help cancer spread, and it aims to find new ways to block that communication to improve treatments for cancer patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10914106 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between tumors and the body's systems that facilitate cancer spread, known as metastasis. It focuses on how tumors influence local and distant tissues through secreted factors, leading to changes in immune response, metabolism, and organ function. By studying these interactions, the research aims to identify potential therapeutic targets to disrupt the communication between tumors and the body, ultimately improving treatment strategies for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with cancer who are at risk of metastasis or experiencing related systemic effects.
Not a fit: Patients with non-cancerous conditions or those whose cancer is already at an advanced stage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively prevent or reduce cancer metastasis, improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in understanding tumor-host interactions, indicating that this approach could lead to significant advancements in cancer treatment.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Lyden, David Charles — Weill Medical Coll of Cornell Univ
- Study coordinator: Lyden, David Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.