Understanding how cancer medicines work in the body
Molecular Pharmacology Shared Resource
['FUNDING_P30'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-11178785
This resource helps researchers at UC Davis understand how cancer medicines move through the body and affect tumors, aiming to make treatments more precise for patients.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-11178785 on ClinicalTrials.gov |
What this research studies
When you take a medicine, your body processes it in unique ways, and this resource helps scientists understand that journey. It looks at how much of a drug reaches the tumor (pharmacokinetics) and what effects it has on the cancer cells (pharmacodynamics). By studying these details in both lab models and patients, researchers can tailor treatments to be more effective and safer for individuals with cancer. This work supports many cancer clinical trials, helping to develop new and better ways to fight the disease.
Who could benefit from this research
Good fit: Patients participating in cancer clinical trials at UC Davis Comprehensive Cancer Center, whose treatment responses and drug levels are being monitored, are indirectly supported by this resource.
Not a fit: Patients not involved in clinical trials or those whose treatment does not require detailed pharmacokinetic/pharmacodynamic analysis would not directly benefit from this specific resource.
Why it matters
Potential benefit: This resource could lead to more personalized and effective cancer treatments by helping doctors understand the best drug doses and combinations for each patient.
How similar studies have performed: The principles of pharmacokinetics and pharmacodynamics are well-established in drug development, and this resource builds upon decades of successful application in optimizing drug therapies.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YU, AIMING — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: YU, AIMING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.