Understanding how cancer environments affect tumor growth and treatment.
Official title: Cancer Microenvironment Research Program
Funded at University of Rochester · NIH-11014528 · Data updated 2026-11-12
This study is looking at how the tissues around tumors affect cancer growth and treatment, aiming to find ways to boost the immune system and stop cancer from spreading, so that new and better therapies can be developed for patients like you.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | March 15, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $40,527 |
| NIH project number | 1P30CA272302-01A1 |
| Project ID | NIH-11014528 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with cancer, particularly those from rural areas or older adults facing high cancer incidence.
✕Less likely to help
Patients with non-cancerous conditions or those who are not eligible for cancer treatment may not benefit from this research.
What this research studies
The Cancer Microenvironment Research Program at the University of Rochester investigates how the surrounding tissue environments influence the development and treatment of cancer. Researchers are focused on identifying key signals that either suppress the immune response to cancer or promote the growth of cancer stem cells. By utilizing advanced genetic models and patient-derived samples, the program aims to disrupt harmful microenvironments and restore normal tissue function. This research combines expertise in immunology, stem cell biology, and nanotechnology to develop innovative therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance the body's ability to fight cancer and improve patient outcomes.
How similar studies have gone: Previous research has shown promise in manipulating cancer microenvironments, indicating that this approach could lead to significant advancements in cancer treatment.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Calvi, Laura M — University of Rochester
- Study coordinator: Calvi, Laura M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.