Understanding how cancer cells manage their energy and growth needs
Investigating how cancer cells maintain redox homeostasis to support biomass production
This study is looking at how cancer cells manage their energy and nutrients to keep growing, focusing on a special molecule called NAD+, and it aims to find new ways to help treat cancer by understanding these processes better.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11001482 on NIH RePORTER |
What this research studies
This research investigates how cancer cells maintain a balance of essential molecules needed for their growth and survival. By examining the metabolism of cancer cells, the study aims to uncover how these cells adapt to their environment and manage their energy resources, particularly focusing on the role of a key molecule called NAD+. The research will explore how cancer cells sustain their growth despite varying demands for nutrients and energy, which could lead to new strategies for targeting cancer metabolism in treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with various types of cancer who are undergoing treatment.
Not a fit: Patients with non-cancerous conditions or those not currently receiving cancer treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that specifically target cancer cell metabolism, potentially improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown promising results in targeting cancer metabolism, indicating that this approach could lead to significant advancements in cancer treatment.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Chang, Sarah M — Harvard Medical School
- Study coordinator: Chang, Sarah M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.