Understanding how cancer cells invade lung tissue

Cancer invasion: reciprocity between the extracellular matrix and intrinsic ERK signaling

['FUNDING_R01'] · UNIVERSITY OF UTAH · NIH-11075240

This study is looking into how certain proteins help lung cancer cells spread, with the hope that understanding these processes can lead to better treatments for patients with lung adenocarcinoma.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF UTAH (nih funded)
Locations1 site (SALT LAKE CITY, UNITED STATES)
Trial IDNIH-11075240 on ClinicalTrials.gov

What this research studies

This research investigates the mechanisms behind lung adenocarcinoma invasion, which is a significant cause of lung cancer-related health issues. The team aims to explore the roles of Tenascin-C and ERK signaling in promoting cancer cell invasion. By examining how these factors interact and influence tumor behavior, the research seeks to uncover new insights into the cellular processes involved in cancer spread. Patients may benefit from a better understanding of these mechanisms, potentially leading to new therapeutic strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with lung adenocarcinoma who are seeking innovative treatment options.

Not a fit: Patients with other types of cancer or those not diagnosed with lung adenocarcinoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that specifically target the mechanisms of cancer invasion, improving outcomes for lung cancer patients.

How similar studies have performed: Previous research has shown promising results in understanding cancer invasion mechanisms, suggesting that this approach may yield valuable insights.

Where this research is happening

SALT LAKE CITY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: cancer cell

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.