Understanding how cancer cell communication affects pancreatic cancer progression
Official title: Unraveling the functional contribution of extracellular vesicles in pancreatic cancer
Funded at University of Tx Md Anderson Can Ctr · NIH-10571036 · Data updated 2026-11-12
This study is looking at tiny particles released by cancer cells to see how they help pancreatic cancer grow and spread, with the hope of finding new ways to treat this tough disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 17, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $192,240 |
| NIH project number | 1K22CA276360-01 |
| Project ID | NIH-10571036 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with metastatic pancreatic adenocarcinoma who are seeking new treatment options.
✕Less likely to help
Patients with early-stage pancreatic cancer or those not diagnosed with pancreatic cancer may not benefit from this research.
What this research studies
This research investigates the role of extracellular vesicles (EVs) released by cancer cells in the progression of pancreatic cancer. By using genetically engineered mouse models, the study aims to track how these vesicles influence the tumor microenvironment and contribute to cancer initiation and metastasis. The research will focus on the mechanisms of EV release and their effects on surrounding tissues, which could lead to new therapeutic strategies for treating pancreatic cancer.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that effectively target pancreatic cancer by disrupting the communication between cancer cells and their environment.
How similar studies have gone: Previous research has shown promise in targeting extracellular vesicles in other cancer types, suggesting potential for success in this novel approach for pancreatic cancer.
Where this research is happening
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University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Mcandrews, Kathleen — University of Tx Md Anderson Can Ctr
- Study coordinator: Mcandrews, Kathleen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.