Understanding how cancer affects men and women differently
Genetic mechanisms underlying sexual dimorphism in cancer and response to therapy
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-11280610
This study is looking at how cancer affects men and women differently, including how often it occurs, how well people respond to treatment, and what might cause these differences, all to help improve cancer care for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11280610 on ClinicalTrials.gov |
What this research studies
This research investigates the differences in cancer incidence, prognosis, and treatment responses between males and females. By analyzing data from The Cancer Genome Atlas, the study aims to uncover the molecular mechanisms that contribute to these disparities. It will explore gene expression variations and genetic factors that may influence cancer susceptibility in both sexes. The ultimate goal is to enhance precision medicine approaches in cancer treatment by identifying novel biomarkers and therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with common cancers who are interested in understanding how their sex may influence their disease and treatment outcomes.
Not a fit: Patients with rare cancers or those who do not identify as male or female may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments tailored to the specific needs of male and female patients.
How similar studies have performed: Other research has shown promising results in understanding sex differences in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STRANGER, BARBARA E — UNIVERSITY OF COLORADO DENVER
- Study coordinator: STRANGER, BARBARA E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.